Global Working Solutions
Currently, there are over 50 companies working on numerous approaches to improve efficacy and reduce ISR.
Improved stent architectures
New metal alloys and polymer coats
More efficient Drug-Eluting Stents (DES)
MangoGen has invented a new bio-therapeutic delivery mechanism that utilizes a genetically engineered insect virus (baculovirus) encapsulated in a protective nanoparticle. Attached to a suitable matrix, the nanoparticle-encapsulated virus can deliver a specific gene to a very exact location within the body.
Our first application is to address wound healing and re-endothelization of a stented blood vessel.
The baculovirus is a very safe and relatively cheap vehicle that can deliver designed genetic therapy and treatments to a local site (e.g. endothelium).